Adverse effects of vasectomy: sperm granuloma of epididymides.
نویسنده
چکیده
Rats and mice were vasectomized to study the pathological changes in the development and resolution of vasectomy induced sperm granuloma. Epididymal weights were increased in all groups of vasectomized animals, whereas testicular weights did not change. Granuloma in the form of yellow nodular masses of cysts were present at the lower pole of the epididymis. It consisted of a pool of sperm and other material surrounded by a wall of histocytes or macrophages. The biologic significance of the phenomena has been discussed.
منابع مشابه
Quantitative (stereological) study of the effects of vasectomy on spermatogenesis in rhesus monkeys (Macaca mulatta).
Vasectomy reversal by vasovasostomy after long-term vasectomy in men results in lower sperm counts and pregnancy rates compared with controls, and severe damage to spermatogenesis has been observed in some animal models such as mice. The primary aim of this study was to evaluate, using sophisticated stereological methods, whether vasectomy of 6 and 12 months in a non-human primate would lead to...
متن کاملEffect of short period vasectomy on FSH, LH, inhibin and testosterone secretions, and sperm motility in adult male rats.
The present study was undertaken to clarify changes in secretions of FSH, LH, inhibin and testosterone, and sperm motility after bilateral vasectomy in adult male rats. Bilateral vasectomy was created surgically (treated group) and intact rats were used as control (control group). On days 3, 5, 7, 14, 30, 60, and 90 after surgery, plasma concentrations of FSH, LH, inhibin, and testosterone were...
متن کاملMorphometric study of the testis and reproductive tract (including sperm granuloma) after vasectomy in mature rats
By utilizing the rabbit model, previous studies have found good evidence indicating that vasectomy-induced spermatogenic damage is pressure-mediated: the damage occurs when the occluded reproductive tract is unable to accommodate additional spermatozoa produced by the testis. More studies with the more commonly used rat model have shown, however, controversial results on whether and why the dam...
متن کاملScrotal haematoma: the most common complication of no-scalpel vasectomy.
OBJECTIVE to study the complications of no scalpel vasectomy such as scrotal haematoma, infection, scrotal sinus, and failure, recanalization, and sperm granuloma. MATERIALS AND METHODS A retrospective, descriptive study carried out in Dept. of Obs/ Gyn, Tribhuvan University Teaching Hospital Kathmandu Nepal. RESULT Among 926 no scalpel vasectomy clients 5(0.53%) had scrotal haematoma, 4(0....
متن کاملThe Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice Efectos de la Vasectomía sobre la Morfología del Epidídimo y los Parámetros Espermáticos en Ratones Balb/c Adultos
Vasectomy is a common contraceptive procedure in men. The present study is aimed to explore the impact of vasectomy on epididymal morphology and sperm parameters in adult male Balb/c mice. Twenty adult (age: 8 weeks) male Balb/c mice, weighting 20-30 g were used in the experiments. They were divided into 2 groups (vasectomy and sham). The operations were performed under sodium pentobarbital (40...
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ورودعنوان ژورنال:
- Indian journal of physiology and pharmacology
دوره 21 2 شماره
صفحات -
تاریخ انتشار 1977